BAG1_HUMAN   Q99933


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UniProt:Q99933

Recommended name:BAG family molecular chaperone regulator 1

EC number:

Alternative names:(BAG-1) (Bcl-2-associated athanogene 1)

Cleaved into:

GeneID:573

Gene names  (primary ):BAG1

Gene names  (synonym ):HAP

Gene names  (ORF ):

Length:345

Mass:38779

Sequence:MAQRGGARRPRGDRERLGSRLRALRPGREPRQSEPPAQRGPPPSGRPPARSTASGHDRPTRGAAAGARRPRMKKKTRRRSTRSEELTRSEELTLSEEATWSEEATQSEEATQGEEMNRSQEVTRDEESTRSEEVTREEMAAAGLTVTVTHSNEKHDLHVTSQQGSSEPVVQDLAQVVEEVIGVPQSFQKLIFKGKSLKEMETPLSALGIQDGCRVMLIGKKNSPQEEVELKKLKHLEKSVEKIADQLEELNKELTGIQQGFLPKDLQAEALCKLDRRVKATIEQFMKILEEIDTLILPENFKDSRLKRKGLVKKVQAFLAECDTVEQNICQETERLQSTNFALAE

Tissue specificity:Isoform 4 is the most abundantly expressed isoform. It is ubiquitously expressed throughout most tissues, except the liver, colon, breast and uterine myometrium. Isoform 1 is expressed in the ovary and testis. Isoform 4 is expressed in several types of tumor cell lines, and at consistently high levels in leukemia and lymphoma cell lines. Isoform 1 is expressed in the prostate, breast and leukemia cell lines. Isoform 3 is the least abundant isoform in tumor cell lines (at protein level). {ECO:0000269|PubMed:9679980}.

Induction:Up-regulated during differentiation of bladder epithelial cells and down-regulated during differentiation of prostate epithelium. {ECO:0000269|PubMed:9679980}.

Developmental stage:

Protein families:


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