FGFP1_HUMAN Q14512
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UniProt:Q14512
Recommended name:Fibroblast growth factor-binding protein 1
EC number:
Alternative names:(FGF-BP) (FGF-BP1) (FGF-binding protein 1) (FGFBP-1) (17 kDa heparin-binding growth factor-binding protein) (17 kDa HBGF-binding protein) (HBp17)
Cleaved into:
GeneID:9982
Gene names (primary ):FGFBP1
Gene names (synonym ):FGFBP HBP17
Gene names (ORF ):
Length:234
Mass:26264
Sequence:MKICSLTLLSFLLLAAQVLLVEGKKKVKNGLHSKVVSEQKDTLGNTQIKQKSRPGNKGKFVTKDQANCRWAATEQEEGISLKVECTQLDHEFSCVFAGNPTSCLKLKDERVYWKQVARNLRSQKDICRYSKTAVKTRVCRKDFPESSLKLVSSTLFGNTKPRKEKTEMSPREHIKGKETTPSSLAVTQTMATKAPECVEDPDMANQRKTALEFCGETWSSLCTFFLSIVQDTSC
Tissue specificity:Expressed in the suprabasal region of the epidermis, in hair follicles, the basement membrane at the dermo-epidermal junction (occasionally extending into the basement membrane of dermal blood vessels), wounded skin and several invasive squamous cell carcinomas (at protein level). Expressed in normal and wounded skin and various squamous cell carcinomas. {ECO:0000269|PubMed:11148217, ECO:0000269|PubMed:15806171, ECO:0000269|PubMed:1885605}.
Induction:Up-regulated in epithelial cells after skin injury. Keratinocyte mitogens. {ECO:0000269|PubMed:15806171}.
Developmental stage:
Protein families:Fibroblast growth factor-binding protein family