PA21B_MOUSE   Q9Z0Y2


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UniProt:Q9Z0Y2

Recommended name:Phospholipase A2

EC number:EC 3.1.1.4

Alternative names:(Group IB phospholipase A2) (PLA2-Ib) (Phosphatidylcholine 2-acylhydrolase 1B)

Cleaved into:

GeneID:18778

Gene names  (primary ):Pla2g1b

Gene names  (synonym ):Pla2

Gene names  (ORF ):

Length:146

Mass:16290

Sequence:MKLLLLAALLTAGAAAHSISPRAVWQFRNMIKCTIPGSDPLKDYNNYGCYCGLGGWGTPVDDLDRCCQTHDHCYSQAKKLESCKFLIDNPYTNTYSYSCSGSEITCSAKNNKCEDFICNCDREAAICFSKVPYNKEYKNLDTGKFC

Tissue specificity:Expressed in pancreas, liver, lung and spleen (PubMed:10066760). Expressed in EPCAM-positive intestinal epithelial cell (at protein level) (PubMed:29024642). {ECO:0000269|PubMed:10066760, ECO:0000269|PubMed:29024642}.

Induction:Up-regulated in EPCAM-positive intestinal epithelial cell upon helminth infection (PubMed:29024642). Up-regulated in intestinal epithelial organoids in response to stimulation with T-helper type 2 cytokines IL4 and IL13 (PubMed:29024642). {ECO:0000269|PubMed:29024642}.

Developmental stage:

Protein families:Phospholipase A2 family


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