MAK_MOUSE Q04859
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UniProt:Q04859
Recommended name：Serine/threonine-protein kinase MAK
EC number：EC 2.7.11.1
Alternative names：(Male germ cell-associated kinase) (Protein kinase RCK)
Cleaved into：
GeneID：17152
Gene names (primary )：Mak
Gene names (synonym )：Rck
Gene names (ORF )：
Length：622
Mass：70080
Sequence：MNRYTTMKQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHANVIKLKEVIRENDHLYFVFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHGFFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSVYSSPIDVWAVGSIMAELYTFRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQCIPINLKTLIPNASSEAIQLMTEMLNWDPKKRPTASQALKHPYFQVGQVLGSSAHHLDTKQTLHKQLQPLEPKPSSSERDPKPLPNILDQPAGQPQPKQGHQPLQTIQPPQNTVTHPPPKQQGHQKPPQTMFPSIIKTIPVNSVSTLGHKGARRRWGQTVFKSGDSCDDIEDDLGASHSKKPSMEACKEKKKESPFRFPDSGLPVSNHFKGENRNLHASVSLKSDPNLSTASTAKQYYLKQSRYLPGVNPKNVSLVAGGKDINSHSWNNQLFPKSLGSMGADLSFKRSNAAGNLGSYTTYNQTGYMPSFLKKEVGSAGQRIQLAPLGASASDYTWSTKTGRGQFSGRTYNPTAKNLNIVNRTQPVPSVHGRTDWVAKYGGHR
Tissue specificity：In pre- and postmeiotic male germ cells in testis. In photoreceptor cells of the retina and in the olfactory receptors, and in certain epithelia of the respiratory tract and choroid plexus (brain). {ECO:0000269|PubMed:21148103}.
Induction：
Developmental stage：On day 14 or 17 of embryonic development. Expression is observed in germ cells at the stages of late pachytene spermatocytes through to early round spermatids. {ECO:0000269|PubMed:1473268}.
Protein families：Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily