SEP12_HUMAN Q8IYM1
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UniProt:Q8IYM1
Recommended name：Septin-12
EC number：
Alternative names：
Cleaved into：
GeneID：124404
Gene names (primary )：SEPTIN12
Gene names (synonym )：44451
Gene names (ORF )：
Length：358
Mass：40748
Sequence：MDPLRRSPSPCLSSQPSSPSTPPCEMLGPVGIEAVLDQLKIKAMKMGFEFNIMVVGQSGLGKSTMVNTLFKSKVWKSNPPGLGVPTPQTLQLHSLTHVIEEKGVKLKLTVTDTPGFGDQINNDNCWDPILGYINEQYEQYLQEEILITRQRHIPDTRVHCCVYFVPPTGHCLRPLDIEFLQRLCRTVNVVPVIARADSLTMEEREAFRRRIQQNLRTHCIDVYPQMCFDEDINDKILNSKLRDRIPFAVVGADQEHLVNGRCVLGRKTKWGIIEVENMAHCEFPLLRDLLIRSHLQDLKDITHNIHYENYRVIRLNESHLLPRGPGWVNLAPASPGQLTTPRTFKVCRGAHDDSDDEF
Tissue specificity：Widely expressed. Expressed in lymph node. {ECO:0000269|PubMed:15915442, ECO:0000269|PubMed:17967425}.
Induction：
Developmental stage：At the first step of spermiogenesis concentrated around the acrosome. Afterwards expressed between the edge of the acrosome and the perinuclear mantle of the manchette. Next, encircles the upper site of the acrosome and forms the rim of the sperm nucleus. With the formation of mitochondria and mature spermatozoa, localized at the neck and annulus regions. {ECO:0000269|PubMed:20801438}.
Protein families：TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily, Septin GTPase family