SIA4B_MOUSE Q11204
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UniProt:Q11204
Recommended name:CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2
EC number:EC 2.4.99.4
Alternative names:(Alpha 2,3-ST 2) (Beta-galactoside alpha-2,3-sialyltransferase 2) (Gal-NAc6S) (Gal-beta-1,3-GalNAc-alpha-2,3-sialyltransferase) (Monosialoganglioside sialyltransferase) (ST3Gal II) (ST3GalII) (ST3GalA.2) (Sialyltransferase 4B) (SIAT4-B)
Cleaved into:
GeneID:20444
Gene names (primary ):St3gal2
Gene names (synonym ):Siat4b Siat5
Gene names (ORF ):
Length:350
Mass:40130
Sequence:MKCSLRVWFLSMAFLLVFIMSLLFTYSHHSMATLPYLDSGALGGTHRVKLVPGYSGLQRLGKEGLLGRNCACSRCMGDASTSEWFDSHFDGNISPVWTRDNMNLPPDVQRWWMMLQPQFKSHNTNEVLEKLFQIVPGENPYRFRDPQQCRRCAVVGNSGNLRGSGYGQEVDSHNFIMRMNQAPTVGFEKDVGSRTTHHFMYPESAKNLPANVSFVLVPFKALDLMWIASALSTGQIRFTYAPVKSFLRVDKEKVQIYNPAFFKYIHDRWTEHHGRYPSTGMLVLFFALHVCDEVNVYGFGADSRGNWHHYWENNRYAGEFRKTGVHDADFEAHIIDMLAKASKIEVYRGN
Tissue specificity:Strongly expressed in brain and liver and to a lesser extent in heart and kidney. Scarcely detectable in lung, pancreas, spleen and submaxillary gland (PubMed:8144500). Expressed in L5 dorsal root ganglion (DRG) neurons (at protein level) (PubMed:32030804). {ECO:0000269|PubMed:32030804, ECO:0000269|PubMed:8144500}.
Induction:Up-regulated in DRG neurons in response to nerve injury. {ECO:0000269|PubMed:32030804}.
Developmental stage:
Protein families:Glycosyltransferase 29 family