RAI14_MOUSE Q9EP71
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UniProt:Q9EP71
Recommended name：Ankycorbin
EC number：
Alternative names：(Ankyrin repeat and coiled-coil structure-containing protein) (Novel retinal pigment epithelial cell protein) (Retinoic acid-induced protein 14) (p125)
Cleaved into：
GeneID：75646
Gene names (primary )：Rai14
Gene names (synonym )：Kiaa1334 Norpeg
Gene names (ORF )：
Length：979
Mass：108852
Sequence：MKSLKAKFRKSDTNEWNKNDDRLLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLKVMVTHGVDVTAQDSSGHSALHVAAKNGHPECIRKLLQYKSPAENIDNSGKTALHYAAAQGCLQAVQLLCEHKSPINLKDLDGNIPLLVAVQNGHSEACHFLLDHGADVNSRDKNGRTALMLACETGSSNTVDALIKKGADLSLVDSLGHNALHYSKLSENAGIQNLLLSKISQDADLKTPTKPKQHDQVSKISSERSGTPKKRKAPPPPISPTQLSDVSSPRSITSTPLSGKESVFFAEAPFKAEISSIQENKDRLSDSTAGADSLLDISSEADQQDLLVLLQAKVASLTLHNKELQDKLQAKSPKDKEAEADLSFQSFHSTQTDLAPSPGKASDIPSSDAKSSPPVEHPAGTSTTDNDVIIRQLQDSLHDLQKRLESSEAEKKQLQDELQSQRTDTLCLNNTEISENGSDLSQKLKETQSKYEEAMKEVLSVQKQMKLGLLSQESADGYSHLREAPADEDIDTLKQDLQKAVEESARNKERVRELETKLAEKEQAEATKPPAEACEELRSSYCSVIENMNKEKAFLFEKYQQAQEEIMKLKDTLKSQMPQEAPDDSGDMKEAMNRMIDELNKQVSELSQLYREAQAELEDYRKRKSLEDAAEYIHKAEHERLMHVSNLSRAKSEEALSEMKSQYSKVLNELTQLKQLVDAHKENSVSITEHLQVITTLRTTAKEMEEKISALTGHLANKEAEVAKLEKQLAEEKAAVSDAMVPKSSYEKLQASLESEVNALATKLKESVREREKAHSEVAQVRSEVSQARREKDNIQTLLKAKEQEVTALVQKFQRAQEELAGMRRCSETSSKLEEDKDEKINEMTREVLKLKEALNSLSQLSYSTSSSKRQSQQLDLLQQQVKQLQNQLAECKKHHQEVISVYRMHLLYAVQGQMDEDVQKVLKQILTMCKNQSQKK
Tissue specificity：Highly expressed in testis, where it localizes to seminiferous tubules (at protein level) (PubMed:11042181, PubMed:16806700). Expressed in ganglion cell layer and in Muller cell fibers of the retina (at protein level) (PubMed:11042181, PubMed:16806700). In small intestine highly expressed at the apical and lateral borders of absorptive epithelia (at protein level) (PubMed:11168586). In liver highly expressed along the bile canaliculi (at protein level) (PubMed:11168586). {ECO:0000269|PubMed:11042181, ECO:0000269|PubMed:11168586, ECO:0000269|PubMed:16806700}.
Induction：
Developmental stage：At 9.5 days, expression is detected in branchial arch mesenchyme, forebrain, hindbrain, midbrain, and neural tube. At 12.5 days, is detected in the hindbrain, forebrain, lung, genital eminence, spinal ligaments around vertebrae and ribs, and around the cartilage of ribs and nasal sinuses. Also detected in frontonasal mass, mandibular arch, optic sulcus, spinal ganglia and hind limb bud. At 15.5 days, expression is detected in the ventricular layer of neurons subjacent to the neocortex, around the nasal sinuses, bronchioles of the lung, kidney, and around the vertebrae of the tail. Also seen in the olfactory bulb. {ECO:0000269|PubMed:11042181}.
Protein families：