HEPS_MOUSE O35453
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UniProt:O35453
Recommended name:Serine protease hepsin
EC number:EC 3.4.21.106
Alternative names:
Cleaved into:Serine protease hepsin non-catalytic chain; Serine protease hepsin catalytic chain
GeneID:15451
Gene names (primary ):Hpn
Gene names (synonym ):
Gene names (ORF ):
Length:436
Mass:46821
Sequence:MAKEDEEPGAHRGGSTCSRPQPGKGGRTAACCSRPKVAALIVGTLLFLTGIGAASWAIVTILLQSDQEPLYQVQLSPGDSRLAVFDKTEGTWRLLCSSRSNARVAGLGCEEMGFLRALAHSELDVRTAGANGTSGFFCVDEGGLPLAQRLLDVISVCDCPRGRFLTATCQDCGRRKLPVDRIVGGQDSSLGRWPWQVSLRYDGTHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGAVARTSPHAVQLGVQAVIYHGGYLPFRDPTIDENSNDIALVHLSSSLPLTEYIQPVCLPAAGQALVDGKVCTVTGWGNTQFYGQQAMVLQEARVPIISNEVCNSPDFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISGTSRWRLCGIVSWGTGCALARKPGVYTKVTDFREWIFKAIKTHSEASGMVTQP
Tissue specificity:Detected in kidney, in thick ascending tubule epithelial cells (at protein level) (PubMed:26673890). Detected in kidney and liver (PubMed:9395459, PubMed:9435303). {ECO:0000269|PubMed:9395459, ECO:0000269|PubMed:9435303}.
Induction:
Developmental stage:
Protein families:Peptidase S1 family