HEPS_MOUSE   O35453


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UniProt:O35453

Recommended name:Serine protease hepsin

EC number:EC 3.4.21.106

Alternative names:

Cleaved into:Serine protease hepsin non-catalytic chain; Serine protease hepsin catalytic chain

GeneID:15451

Gene names  (primary ):Hpn

Gene names  (synonym ):

Gene names  (ORF ):

Length:436

Mass:46821

Sequence:MAKEDEEPGAHRGGSTCSRPQPGKGGRTAACCSRPKVAALIVGTLLFLTGIGAASWAIVTILLQSDQEPLYQVQLSPGDSRLAVFDKTEGTWRLLCSSRSNARVAGLGCEEMGFLRALAHSELDVRTAGANGTSGFFCVDEGGLPLAQRLLDVISVCDCPRGRFLTATCQDCGRRKLPVDRIVGGQDSSLGRWPWQVSLRYDGTHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGAVARTSPHAVQLGVQAVIYHGGYLPFRDPTIDENSNDIALVHLSSSLPLTEYIQPVCLPAAGQALVDGKVCTVTGWGNTQFYGQQAMVLQEARVPIISNEVCNSPDFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISGTSRWRLCGIVSWGTGCALARKPGVYTKVTDFREWIFKAIKTHSEASGMVTQP

Tissue specificity:Detected in kidney, in thick ascending tubule epithelial cells (at protein level) (PubMed:26673890). Detected in kidney and liver (PubMed:9395459, PubMed:9435303). {ECO:0000269|PubMed:9395459, ECO:0000269|PubMed:9435303}.

Induction:

Developmental stage:

Protein families:Peptidase S1 family


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