P4HTM_MOUSE   Q8BG58


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UniProt:Q8BG58

Recommended name:Transmembrane prolyl 4-hydroxylase

EC number:EC 1.14.11.29

Alternative names:(P4H-TM) (Hypoxia-inducible factor prolyl hydroxylase 4) (HIF-PH4) (HIF-prolyl hydroxylase 4) (HPH-4)

Cleaved into:

GeneID:74443

Gene names  (primary ):P4htm

Gene names  (synonym ):Ph4

Gene names  (ORF ):

Length:503

Mass:57049

Sequence:MAAAVATVQRPEAETVEEASNLQWPLPPEHRPSGAATRPGDSEDAPVRPLCKPRGICSRAYFLVLMVFVHLYLGNVLALLLFVHYSNGDESTDPGPQRREQSPQPVPTLGPLTRLEGIKVGYERKVQVVAGRDHFIRTLSLKPLLFEIPGFLSDEECRLIIHLAQMKGLQRSQILPTEEYEEAMSAMQVSQLDLFQLLDQNHDGRLQLREVLAQTRLGNGRWMTPENIQEMYSAIKADPDGDGVLSLQEFSNMDLRDFHKYMRSHKAESNELVRNSHHTWLHQGEGAHHVMRAIRQRVLRLTRLSPEIVEFSEPLQVVRYGEGGHYHAHVDSGPVYPETICSHTKLVANESVPFETSCRYMTVLFYLNNVTGGGETVFPVADNRTYDEMSLIQDDVDLRDTRRHCDKGNLRVKPQQGTAVFWYNYLPDGQGWVGEVDDYSLHGGCLVTRGTKWIANNWINVDPSRARQALFQQEMARLAREGGMDSQPEWALDRAYSDARVEL

Tissue specificity:Highest expression levels are detected in the eye and brain, especially in the retinal epithelium cells and cortical neurons. Also expressed in skeletal muscle, lung, heart, adrenal gland, kidney, prostate, thyroid and testis. {ECO:0000269|PubMed:27466183}.

Induction:

Developmental stage:

Protein families:


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