ALD1_MOUSE   P21300


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UniProt:P21300

Recommended name:Aldo-keto reductase family 1 member B7

EC number:EC 1.1.1.21

Alternative names:(Aldehyde reductase) (AR) (Aldose reductase-related protein 1) (MVDP) (Vas deferens androgen-dependent protein)

Cleaved into:

GeneID:11997

Gene names  (primary ):Akr1b7

Gene names  (synonym ):Avdp

Gene names  (ORF ):

Length:316

Mass:35988

Sequence:MATFVELSTKAKMPLVGLGTWKSSPGQVKEAVKAAIDAGYRHIDCAYVYHNENEVGEAIQEKIKENAVKREDLFIVSKLWATFFEKSLVKKAFQNTLSDLKLDYLDLYLVHWPQGFQAGNALLPKDNKGKVLLSKSTFLDAWEAMEELVDQGLVKALGISNFNHFQIERLLNKPGLKHKPVTNQIESHPYLTQEKLIQYCQSKGIAVTAYSPLGSPDRPYAKPEDPVVMEIPKIKEIAAKHKKTVAQVLIRFHVQRNVVVIPKSVTPSRIQENLQVFDFQLSEEDMAAILSFNRNWRACDLLDARTEEDYPFHEEY

Tissue specificity:Expressed exclusively in the epithelial cells of the deferent duct. {ECO:0000269|PubMed:1637719}.

Induction:Castration resulted in a marked decrease in the level of the mRNA coding for the protein, whereas administration of testosterone to castrated males resulted in a marked increase. {ECO:0000269|PubMed:2123194}.

Developmental stage:

Protein families:Aldo/keto reductase family


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