I17RC_MOUSE   Q8K4C2


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UniProt:Q8K4C2

Recommended name:Interleukin-17 receptor C

EC number:

Alternative names:(IL-17 receptor C) (IL-17RC) (Interleukin-17 receptor-like protein) (IL-17RL) (ZcytoR14)

Cleaved into:

GeneID:171095

Gene names  (primary ):Il17rc

Gene names  (synonym ):

Gene names  (ORF ):

Length:698

Mass:77148

Sequence:MPVSWFLLSLALGRNPVVVSLERLMEPQDTARCSLGLSCHLWDGDVLCLPGSLQSAPGPVLVPTRLQTELVLRCPQKTDCALCVRVVVHLAVHGHWAEPEEAGKSDSELQESRNASLQAQVVLSFQAYPIARCALLEVQVPADLVQPGQSVGSAVFDCFEASLGAEVQIWSYTKPRYQKELNLTQQLPDCRGLEVRDSIQSCWVLPWLNVSTDGDNVLLTLDVSEEQDFSFLLYLRPVPDALKSLWYKNLTGPQNITLNHTDLVPCLCIQVWSLEPDSERVEFCPFREDPGAHRNLWHIARLRVLSPGVWQLDAPCCLPGKVTLCWQAPDQSPCQPLVPPVPQKNATVNEPQDFQLVAGHPNLCVQVSTWEKVQLQACLWADSLGPFKDDMLLVEMKTGLNNTSVCALEPSGCTPLPSMASTRAARLGEELLQDFRSHQCMQLWNDDNMGSLWACPMDKYIHRRWVLVWLACLLLAAALFFFLLLKKDRRKAARGSRTALLLHSADGAGYERLVGALASALSQMPLRVAVDLWSRRELSAHGALAWFHHQRRRILQEGGVVILLFSPAAVAQCQQWLQLQTVEPGPHDALAAWLSCVLPDFLQGRATGRYVGVYFDGLLHPDSVPSPFRVAPLFSLPSQLPAFLDALQGGCSTSAGRPADRVERVTQALRSALDSCTSSSEAPGCCEEWDLGPCTTLE

Tissue specificity:Highly expressed in colonic epithelial cells (PubMed:19144317). Expressed in lung epithelial cells (PubMed:28813677). Expressed in macrophages (PubMed:19144317). Highly expressed in B-1a B cells and at a lower extent in B-1b and B-2 B cells (at protein level) (PubMed:26735852). {ECO:0000269|PubMed:19144317, ECO:0000269|PubMed:26735852, ECO:0000269|PubMed:28813677}.

Induction:Induced in lung epithelial cells upon bacterial and fungal infection. Up-regulated in lung epithelial cells by IL17F; this might account for a persistent activation via a positive feedback loop. {ECO:0000269|PubMed:28813677}.

Developmental stage:

Protein families:


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