KAPCA_MOUSE P05132
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UniProt:P05132
Recommended name:cAMP-dependent protein kinase catalytic subunit alpha
EC number:EC 2.7.11.11
Alternative names:(PKA C-alpha) (EC 2.7.11.11)
Cleaved into:
GeneID:18747
Gene names (primary ):Prkaca
Gene names (synonym ):Pkaca
Gene names (ORF ):
Length:351
Mass:40571
Sequence:MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWETPSQNTAQLDQFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF
Tissue specificity:Isoform 2 is sperm specific.
Induction:
Developmental stage:Accumulates in oocytes before fertilization but fades out after fertilization. {ECO:0000269|PubMed:18367160}.
Protein families:Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamily