K2C71_MOUSE Q9R0H5
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UniProt:Q9R0H5
Recommended name:Keratin, type II cytoskeletal 71
EC number:
Alternative names:(Cytokeratin-6G) (CK-6G) (Cytokeratin-71) (CK-71) (Keratin-6G) (K6G) (Keratin-71) (K71) (Type II inner root sheath-specific keratin-K6irs1) (mK6irs) (mK6irs1/Krt2-6g) (Type-II keratin Kb34)
Cleaved into:
GeneID:56735
Gene names (primary ):Krt71
Gene names (synonym ):K6irs1 Kb34 Krt2-6g Krt6g
Gene names (ORF ):
Length:524
Mass:57383
Sequence:MSRQFTCKSGASNRGFSGCSAVLSGGSSSSYRAGGKGLSGGFGSRSLYSLGGGRSITLNMASGSGKNGGFGFGRNRASGFAGSIFGSVALGPVCPAVCPPGGIHQVTVNESLLAPLNVELDPEIQKVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLQTKWELLQQLDLNNCKNNLEPILEGHISNMRKQLETLSGDRVRLDSELRNVRDVVEDYKKKYEEEINRRTAAENEFVLLKKDVDAAYANKVELQAKVDTMDQDIKFFKCLFEAEMAQIQSHISDMSVILSMDNNRNLDLDSIIDEVRAQYEEIALKSKAEAEALYQTKFQELQLAAGRHGDDLKNTKNEITELTRFIQRLRSEIENAKKQASNLETAIADAEQRGDSALKDARAKLDELEGALHQAKEELARMLREYQELMSLKLALDMEIATYRKLLESEECRMSGEYSSPVSISIISSTSGSGGYGFRPSTVSGGYVANSTSCISGVCSVRGGENRSRGSASDYKDTLTKGSSLSTPSKKGGR
Tissue specificity:Specifically expressed in the inner root sheath (IRS) of the hair follicle. Present in Henle and the Huxley layers of the IRS, while expression in the cuticle is unsure (at protein level). {ECO:0000269|PubMed:11231308, ECO:0000269|PubMed:11703281, ECO:0000269|PubMed:14573483}.
Induction:
Developmental stage:Expressed exclusively in the inner root sheath (IRS) of anagen hair follicles, where expression is predominantly in the hair cone during anagen III and in the Huxley and Henle layers of the inner root sheath during anagen VI. {ECO:0000269|PubMed:11231308}.
Protein families:Intermediate filament family