IFNE_MOUSE Q80ZF2
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UniProt:Q80ZF2
Recommended name：Interferon epsilon
EC number：
Alternative names：(IFN-epsilon) (Interferon epsilon-1) (Interferon tau-1)
Cleaved into：
GeneID：230405
Gene names (primary )：Ifne
Gene names (synonym )：Ifne1 Ifnt1
Gene names (ORF )：
Length：192
Mass：22372
Sequence：MVHRQLPETVLLLLVSSTIFSLEPKRIPFQLWMNRESLQLLKPLPSSSVQQCLAHRKNFLLPQQPVSPHQYQEGQVLAVVHEILQQIFTLLQTHGTMGIWEENHIEKVLAALHRQLEYVESLGGLNAAQKSGGSSAQNLRLQIKAYFRRIHDYLENQRYSSCAWIIVQTEIHRCMFFVFRFTTWLSRQDPDP
Tissue specificity：Expressed at very high levels in uterus and, at much lower levels, in ovary and cervix. Very low levels, if any, in other organs. In the endometrium, expressed in the luminal and glandular epithelial cells (at protein level). {ECO:0000269|PubMed:15233997, ECO:0000269|PubMed:23449591}.
Induction：By estrogens. Contrary to other type I interferons, not induced by known pattern-recognition receptor pathways. {ECO:0000269|PubMed:23449591}.
Developmental stage：Expression varies approximately 30-fold during the estrous cycle, with lowest levels during diestrus and highest at estrus. During pregnancy, uterine expression is dramatically reduced at 1.5 dpc and reaches its lowest levels at 4.5 dpc, coincident with the time of embryo implantation. {ECO:0000269|PubMed:23449591}.
Protein families：Alpha/beta interferon family