ELAV4_RAT O09032
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UniProt:O09032
Recommended name:ELAV-like protein 4
EC number:
Alternative names:
Cleaved into:
GeneID:
Gene names (primary ):Elavl4
Gene names (synonym ):Hud
Gene names (ORF ):
Length:385
Mass:42,368
Sequence:MEWNGLKMIISTMEPQVSNGPTSNTSNGPSSNNRNCPSPMQTGAATDDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRLMSGPVPPSACPPRFSPITIDGMTSLVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKAHKS
Tissue specificity:Expressed in the hippocampus and cerebral cortex (at protein level) (PubMed:15519747). Expressed in stem and progenitor cells in the subventricular zone of the hippocampus (at protein level) (PubMed:16554442). Expressed in hippocampal neurons, with highest levels of expression in the CA4 and CA3 neurons and lower levels in CA1 neurons (at protein level) (PubMed:11948657, PubMed:17577668, PubMed:25692578). Expressed in the dorsal root ganglion (at protein level) (PubMed:12957493). Expressed in the superior cervical ganglion (PubMed:17234598). 7 s
Induction:Expression in dentate granule cells of the hippocampus at postnatal day 7, with disappearing expression in dentate granule cells as early as P14. 1 Publication
Developmental stage:Up-regulated by kainic acid-induced seizures (PubMed:17577668). Up-regulated after contextual fear conditioning (PubMed:15519747). Down-regulated at day 2 after axotomy and up-regulated at day 7 after axotomy (PubMed:12957493, PubMed:17234598). 4 s
Protein families:RRM elav family