GPM6A_MOUSE P35802
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UniProt:P35802
Recommended name：Neuronal membrane glycoprotein M6-a
EC number：
Alternative names：(M6a)
Cleaved into：
GeneID：234267
Gene names (primary )：Gpm6a
Gene names (synonym )：M6a
Gene names (ORF )：
Length：278
Mass：31149
Sequence：MEENMEEGQTQKGCFECCIKCLGGIPYASLIATILLYAGVALFCGCGHEALSGTVNILQTYFELARTAGDTLDVFTMIDIFKYVIYGIAAAFFVYGILLMVEGFFTTGAIKDLYGDFKITTCGRCVSAWFIMLTYLFMLAWLGVTAFTSLPVYMYFNVWTICRNTTLVEGANLCLDLRQFGIVTIGEEKKICTASENFLRMCESTELNMTFHLFIVALAGAGAAVIAMVHYLMVLSANWAYVKDACRMQKYEDIKSKEEQELHDIHSTRSKERLNAYT
Tissue specificity：Widely expressed in the CNS. Found especially in the granule cell layer of the cerebellum but not in the molecular layer or white matter. Expressed in the immature embryonic retina including the nerve fiber layer (NFL), inner plexiform layer (IPL), and outer plexiform layer (OPL). Weakly expressed in processes of Mueller glia cells. {ECO:0000269|PubMed:18776950}.
Induction：
Developmental stage：First detected in presumptive postmitotic neurons in the developing neural tube at embryonic day 9. Expressed in 14 dpc retinas, and expression continued after birth with a slight decrease between P12 and P15. In the 14 dpc retina is mainly and strongly expressed in the NFL. In P1 and P5 retinas strong expression is confined to the IPL and also in NFL. At P10 and in the adult retina strong expression is detected in the IPL, and weak expression in NFL, OPL, and inner nuclear layer. Is expressed on postmitotic mature neurons. {ECO:0000269|PubMed:18776950}.
Protein families：Myelin proteolipid protein family