KCAB2_MOUSE P62482
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UniProt:P62482
Recommended name：Voltage-gated potassium channel subunit beta-2
EC number：EC 1.1.1.-
Alternative names：(K(+) channel subunit beta-2) (Kv-beta-2) (Neuroimmune protein F5)
Cleaved into：
GeneID：16498
Gene names (primary )：Kcnab2
Gene names (synonym )：Ckbeta2 I2rf5 Kcnb3
Gene names (ORF )：
Length：367
Mass：41021
Sequence：MYPESTTGSPARLSLRQTGSPGMIYSTRYGSPKRQLQFYRNLGKSGLRVSCLGLGTWVTFGGQITDEMAEHLMTLAYDNGINLFDTAEVYAAGKAEVVLGNIIKKKGWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRPDPNTPMEETVRAMTHVINQGMAMYWGTSRWSSMEIMEAYSVARQFNLIPPICEQAEYHMFQREKVEVQLPELFHKIGVGAMTWSPLACGIVSGKYDSGIPPYSRASLKGYQWLKDKILSEEGRRQQAKLKELQAIAERLGCTLPQLAIAWCLRNEGVSSVLLGASNAEQLMENIGAIQVLPKLSSSIVHEIDSILGNKPYSKKDYRS
Tissue specificity：Detected in brain (PubMed:21357749). Detected at basket cell terminals in cerebellum and in the juxtaparanodal region of nodes of Ranvier (at protein level) (PubMed:11825900). Strongest expression in brain and eye. Highest levels in brain detected in brainstem and diencephalon. Strong expression also detected in lung and heart. Moderate expression in kidney, T-lymphocytes and skeletal muscle. {ECO:0000269|PubMed:11825900, ECO:0000269|PubMed:1573677, ECO:0000269|PubMed:21357749, ECO:0000269|PubMed:8824288}.
Induction：
Developmental stage：Not detected prior to birth, low levels of expression detected from postnatal days 1 to 7. Expression reaches adult levels by postnatal day 21. {ECO:0000269|PubMed:1573677}.
Protein families：Shaker potassium channel beta subunit family