GIMA4_MOUSE   Q99JY3


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UniProt:Q99JY3

Recommended name:GTPase IMAP family member 4

EC number:

Alternative names:(Immunity-associated nucleotide 1 protein) (IAN-1) (Immunity-associated protein 4)

Cleaved into:

GeneID:107526

Gene names  (primary ):Gimap4

Gene names  (synonym ):Ian1 Imap4

Gene names  (ORF ):

Length:328

Mass:38044

Sequence:MEVQCGGAGFIPESSRSSHELGNQDQGIPQLRIVLLGKTGAGKSSTGNSILGEKVFNSGICAKSITKVCEKRVSTWDGKELVVVDTPGIFDTEVPDADTQREITRYVALTSPGPHALLLVVPLGRYTVEEHKATQKILDMFGKQARRFMILLLTRKDDLEDTDIHEYLEKAPKFFQEVMHEFQNRYCLFNNRASGAEKEEQKMQLLTLVQSMVRENGGRCFTNKMYESAECVIQKETLRMQELYREELEREKARIRREYEEQIKDLRDELEREIRRARMEREFKEREAIFTKNQQNARKEVENTSMILELIIKAWEIASFIFNQFMKD

Tissue specificity:Expressed in thymus (in thymocytes), spleen (in splenocytes), lymph node and lung (PubMed:16509771). Expressed in B-cells and T-cells (at protein level) (PubMed:16569770, PubMed:16509771). {ECO:0000269|PubMed:16509771, ECO:0000269|PubMed:16569770}.

Induction:

Developmental stage:Up-regulated during T cell development, including upon the maturation of CD4/CD8 double-positive to CD4 single-positive thymocytes. {ECO:0000269|PubMed:16509771, ECO:0000269|PubMed:16569770}.

Protein families:TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily, AIG1/Toc34/Toc159-like paraseptin GTPase family, IAN subfamily


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