GIMA4_MOUSE Q99JY3
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UniProt:Q99JY3
Recommended name:GTPase IMAP family member 4
EC number:
Alternative names:(Immunity-associated nucleotide 1 protein) (IAN-1) (Immunity-associated protein 4)
Cleaved into:
GeneID:107526
Gene names (primary ):Gimap4
Gene names (synonym ):Ian1 Imap4
Gene names (ORF ):
Length:328
Mass:38044
Sequence:MEVQCGGAGFIPESSRSSHELGNQDQGIPQLRIVLLGKTGAGKSSTGNSILGEKVFNSGICAKSITKVCEKRVSTWDGKELVVVDTPGIFDTEVPDADTQREITRYVALTSPGPHALLLVVPLGRYTVEEHKATQKILDMFGKQARRFMILLLTRKDDLEDTDIHEYLEKAPKFFQEVMHEFQNRYCLFNNRASGAEKEEQKMQLLTLVQSMVRENGGRCFTNKMYESAECVIQKETLRMQELYREELEREKARIRREYEEQIKDLRDELEREIRRARMEREFKEREAIFTKNQQNARKEVENTSMILELIIKAWEIASFIFNQFMKD
Tissue specificity:Expressed in thymus (in thymocytes), spleen (in splenocytes), lymph node and lung (PubMed:16509771). Expressed in B-cells and T-cells (at protein level) (PubMed:16569770, PubMed:16509771). {ECO:0000269|PubMed:16509771, ECO:0000269|PubMed:16569770}.
Induction:
Developmental stage:Up-regulated during T cell development, including upon the maturation of CD4/CD8 double-positive to CD4 single-positive thymocytes. {ECO:0000269|PubMed:16509771, ECO:0000269|PubMed:16569770}.
Protein families:TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily, AIG1/Toc34/Toc159-like paraseptin GTPase family, IAN subfamily