HYES_MOUSE P34914
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UniProt:P34914
Recommended name:Bifunctional epoxide hydrolase 2 [Includes: Cytosolic epoxide hydrolase 2
EC number:EC 3.3.2.10
Alternative names:(CEH) (Epoxide hydratase) (Soluble epoxide hydrolase) (SEH); Lipid-phosphate phosphatase (EC 3.1.3.76)]
Cleaved into:
GeneID:13850
Gene names (primary ):Ephx2
Gene names (synonym ):Eph2
Gene names (ORF ):
Length:554
Mass:62515
Sequence:MALRVAAFDLDGVLALPSIAGAFRRSEEALALPRDFLLGAYQTEFPEGPTEQLMKGKITFSQWVPLMDESYRKSSKACGANLPENFSISQIFSQAMAARSINRPMLQAAIALKKKGFTTCIVTNNWLDDGDKRDSLAQMMCELSQHFDFLIESCQVGMIKPEPQIYNFLLDTLKAKPNEVVFLDDFGSNLKPARDMGMVTILVHNTASALRELEKVTGTQFPEAPLPVPCNPNDVSHGYVTVKPGIRLHFVEMGSGPALCLCHGFPESWFSWRYQIPALAQAGFRVLAIDMKGYGDSSSPPEIEEYAMELLCKEMVTFLDKLGIPQAVFIGHDWAGVMVWNMALFYPERVRAVASLNTPFMPPDPDVSPMKVIRSIPVFNYQLYFQEPGVAEAELEKNMSRTFKSFFRASDETGFIAVHKATEIGGILVNTPEDPNLSKITTEEEIEFYIQQFKKTGFRGPLNWYRNTERNWKWSCKGLGRKILVPALMVTAEKDIVLRPEMSKNMEKWIPFLKRGHIEDCGHWTQIEKPTEVNQILIKWLQTEVQNPSVTSKI
Tissue specificity:Detected in liver, intestine, ovary and kidney. Detected at low levels in heart and muscle. {ECO:0000269|PubMed:15601917, ECO:0000269|PubMed:21217101, ECO:0000269|PubMed:7840649, ECO:0000269|PubMed:8750907}.
Induction:Up-regulated during the luteal phase of the stimulated estrus cycle and by compounds that cause peroxisome proliferation, such as clofibrate, tiadenol and fenofibrate. {ECO:0000269|PubMed:15601917, ECO:0000269|PubMed:8349642, ECO:0000269|PubMed:8750907}.
Developmental stage:
Protein families:AB hydrolase superfamily, Epoxide hydrolase family