MAFF_MOUSE O54791
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UniProt:O54791
Recommended name:Transcription factor MafF
EC number:
Alternative names:(V-maf musculoaponeurotic fibrosarcoma oncogene homolog F)
Cleaved into:
GeneID:17133
Gene names (primary ):Maff
Gene names (synonym ):
Gene names (ORF ):
Length:156
Mass:16955
Sequence:MAVDPLSSKALKVKRELSENTPHLSDEALMGLSVRELNRNLRGLSAEEVTRLKQRRRTLKNRGYAASCRVKRVCQKEELQKQKSELEREVDKLARENAAMRLELDALRGKCEALQGFARSVAAARGPAALVAPASVITIVKSAPGPAPAADPAPCS
Tissue specificity:Highly expressed in the lung, lower expression in the brain, thymus, liver, spleen, intestine, kidney, heart, muscle, and ovary. Not significantly expressed in hematopoietic cells.
Induction:
Developmental stage:Detected at 6.5 dpc in the boundary between the extraembryonic and embryonic regions. At 8.5 dpc, weakly expressed in the future gut, allantois, yolk sac endoderm and the ectoplacental cone. At 9.5 dpc, strong expression in the primordial gut and presumptive fetal liver, in the floorplate of the myelencephalon, neural crest cells, spongiotrophoblasts, and giant cells of the placenta. At 12.5 dpc, detected in hepotocytes, in the outflow tract of the heart in a specific subset of dorsal root ganglia, in the cranial nerve ganglia, in the lung primordium, and in the epithelium of the expiratory tract. In newborn, strongly expressed in keratinocytes, in the cartilage, in bronchial epithelia, and bone membrane. {ECO:0000269|PubMed:10409670}.
Protein families:BZIP family, Maf subfamily