PR2C2_MOUSE P04095
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UniProt:P04095
Recommended name：Prolactin-2C2
EC number：
Alternative names：(Mitogen-regulated protein 1) (Proliferin-1)
Cleaved into：
GeneID：18811
Gene names (primary )：Prl2c2
Gene names (synonym )：Mrp1 Plf Plf1
Gene names (ORF )：
Length：224
Mass：25367
Sequence：MLPSLIQPCSWILLLLLVNSSLLWKNVASFPMCAMRNGRCFMSFEDTFELAGSLSHNISIEVSELFTEFEKHYSNVSGLRDKSPMRCNTSFLPTPENKEQARLTHYSALLKSGAMILDAWESPLDDLVSELSTIKNVPDIIISKATDIKKKINAVRNGVNALMSTMLQNGDEEKKNPAWFLQSDNEDARIHSLYGMISCLDNDFKKVDIYLNVLKCYMLKIDNC
Tissue specificity：Expressed in brain and cerebellum (PubMed:16876275). Expressed in placenta and hair follicles, with highest expression levels detected in the outer root sheath and no expression detected in bulb (PubMed:11316781, PubMed:10537154). Also expressed in body fluids such as plasma and amniotic fluid (PubMed:10537154). Expressed in embryonic fibroblasts and at low levels in keratinocytes (PubMed:11316781). Isoform 1: Expressed in brain and Neuro-2a cells (PubMed:16876275). Isoform 2: Expressed in brain (PubMed:16876275). {ECO:0000269|PubMed:10537154, ECO:0000269|PubMed:11316781, ECO:0000269|PubMed:16876275}.
Induction：
Developmental stage：Expressed at low levels during hair follicle morphogenesis, with highest expression levels detected at late anagen stage of the hair follicle cycle (PubMed:11316781). Expressed in developing brain from embryo to adult (PubMed:16876275). In placenta, detected at 8 dpc, peaks at 10 dpc and declines thereafter (PubMed:10537154). {ECO:0000269|PubMed:10537154, ECO:0000269|PubMed:11316781, ECO:0000269|PubMed:16876275}.
Protein families：Somatotropin/prolactin family