GSDA3_MOUSE Q5Y4Y6
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UniProt:Q5Y4Y6
Recommended name:Gasdermin-A3
EC number:
Alternative names:(Gasdermin-3)
Cleaved into:Gasdermin-A3, N-terminal (GSDMA3-NT); Gasdermin-A3, C-terminal (GSDMA3-CT)
GeneID:450219
Gene names (primary ):Gsdma3
Gene names (synonym ):Gsdm3
Gene names (ORF ):
Length:464
Mass:52020
Sequence:MPVFEDVTRALVRELNPRGDLTPLDSLIDFKHFRPFCLVLRKRKSTLFWGARYVRTDYTLLDLLEPGSSPSDLTDSGNFSFKNMLDVQVQGLVEVPKTVKVKGTAGLSQSSTLEVQTLSVAPSALENLKKERKLSADHSFLNEMRYHEKNLYVVMEAVEAKQEVTVEQTGNANAIFSLPSLALLGLQGSLNNNKAVTIPKGCVLAYRVRLLRVFLFNLWDIPYICNDSMQTFPKIRRVPCSAFISPTQMISEEPEEEKLIGEMHEDFKTLKEEVQRETQEVEKLSPVGRSSLLTSLSHLLGKKKELQDLEQKLEGALDKGQKVTLEALPKDVLLSKDAMDAILYFLGALTELTEEQLKILVKSLEKKILPVQLKLVESTLEQNFLQDKEGVFPLQPDLLSSLGEEELTLTEALVGLSGLEVQRSGPQYAWDPDTRHNLCALYAGLSLLHLLSRKSNALTYCALS
Tissue specificity:Highest levels in skin with weak expression in placenta and testis. Not detected in the gastrointestinal tract. In skin, expressed in postnatal hair follicles and epidermis as well as sebaceous gland basal cells. {ECO:0000269|PubMed:15475261}.
Induction:
Developmental stage:Not detected at postnatal day 1. Expressed on subsequent postnatal days up to day 20 and throughout adulthood. {ECO:0000269|PubMed:15475261}.
Protein families:Gasdermin family