CCL2_HUMAN   P13500


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UniProt:P13500

Recommended name:C-C motif chemokine 2

EC number:

Alternative names:(HC11) (Monocyte chemoattractant protein 1) (Monocyte chemotactic and activating factor) (MCAF) (Monocyte chemotactic protein 1) (MCP-1) (Monocyte secretory protein JE) (Small-inducible cytokine A2)

Cleaved into:

GeneID:6347

Gene names  (primary ):CCL2

Gene names  (synonym ):MCP1 SCYA2

Gene names  (ORF ):

Length:99

Mass:11025

Sequence:MKVSAALLCLLLIAATFIPQGLAQPDAINAPVTCCYNFTNRKISVQRLASYRRITSSKCPKEAVIFKTIVAKEICADPKQKWVQDSMDHLDKQTQTPKT

Tissue specificity:Expressed in the seminal plasma, endometrial fluid and follicular fluid (at protein level) (PubMed:23765988). Expressed in monocytes (PubMed:2513477). {ECO:0000269|PubMed:23765988, ECO:0000269|PubMed:2513477}.

Induction:Up-regulated upon hypertonic conditions (PubMed:23233732). In pancreatic islets, secretion is stimulated by IL1B (PubMed:23955712). {ECO:0000269|PubMed:23233732, ECO:0000269|PubMed:23955712}.

Developmental stage:

Protein families:Intercrine beta (chemokine CC) family


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