MUC24_HUMAN Q04900
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UniProt:Q04900
Recommended name:Sialomucin core protein 24
EC number:
Alternative names:(MUC-24) (Endolyn) (Multi-glycosylated core protein 24) (MGC-24) (MGC-24v) (CD antigen CD164)
Cleaved into:
GeneID:8763
Gene names (primary ):CD164
Gene names (synonym ):
Gene names (ORF ):
Length:197
Mass:20917
Sequence:MSRLSRSLLWAATCLGVLCVLSADKNTTQHPNVTTLAPISNVTSAPVTSLPLVTTPAPETCEGRNSCVSCFNVSVVNTTCFWIECKDESYCSHNSTVSDCQVGNTTDFCSVSTATPVPTANSTAKPTVQPSPSTTSKTVTTSGTTNNTVTPTSQPVRKSTFDAASFIGGIVLVLGVQAVIFFLYKFCKSKERNYHTL
Tissue specificity:Isoform 1 and isoform 3 are expressed in hematopoietic and non-hematopoietic tissues. Isoform 1 is expressed by prostate cancer tumors and prostate cancer cell lines. The expression is greater in bone metastases than in primary tumors. Expression in osseous metastasis is greater than that in soft tissue metastasis. Isoform 2 is expressed in the small intestine, colon, lung, thyroid and in colorectal and pancreatic adenocarcinoma. Isoform 4 is expressed by both hematopoietic progenitor cells and bone marrow stromal cells. {ECO:0000269|PubMed:10878358, ECO:0000269|PubMed:11027692, ECO:0000269|PubMed:1478919, ECO:0000269|PubMed:16859559, ECO:0000269|PubMed:9763543}.
Induction:Up-regulated by CXCL12 in prostate cancer cell lines. {ECO:0000269|PubMed:16859559}.
Developmental stage:
Protein families:CD164 family