DRC4_MOUSE Q60779
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UniProt:Q60779
Recommended name:Dynein regulatory complex subunit 4
EC number:
Alternative names:(Growth arrest-specific protein 11) (GAS-11) (Growth arrest-specific protein 8) (GAS-8)
Cleaved into:
GeneID:104346
Gene names (primary ):Gas8
Gene names (synonym ):Drc4 Gas11
Gene names (ORF ):
Length:478
Mass:56264
Sequence:MAPKKKGKKGKAKGTAIVDGVAPEDMTKEQVEEHVARIREELDREREERNYFQLERDKIHTFWEITRRQLEEKKAELRNKDREMEEAEERHQVEIKVYKQKVKHLLYEHQNNLAEVKAEGTVVMKLAQKEHRTQEGALRKDMRVLKVELKEQELANEVVIKNLCLKQAEEITKMRNDFERQVREIEAKYDKKMKMLRDELDLRRKTEIHEVEERKNGQISTLMQRHEEAFTDIKNYYNDITLNNLALINSLKEQMEDMRKKEEHMEREMAEVTLQNRRLADPLQKAKDEMNEMQKRLGNHERDKQILVCTKARLKVAERELKDLKWEHEVLEQRFIKVQQEREELYRKFADAIQEVQQKTGFKNLLLERKLQALNAAVEKREVQFNEVLAASNLDPTALTLVSRKLEDVLESKNTTIKDLQYELARVCKAHNDLLRTYEAKLLAFGIPLDNVGFKPLETAVIGQTLGQGPAGLVGAPT
Tissue specificity:Highly expressed in adult testes and lung. Weakly or not expressed in other tested tissues. {ECO:0000269|PubMed:11751847, ECO:0000269|PubMed:18396146}.
Induction:Expressed during serum starvation or contact inhibition of cells grown in murine fibroblasts.
Developmental stage:Weakly or not expressed in neonates and young adolescents. Then, it is strongly expressed postmeiotically. Accumulates in gametocytes as they approach the lumen of seminiferous tubules and thereafter. {ECO:0000269|PubMed:11751847}.
Protein families:DRC4 family