PA2G5_HUMAN   P39877


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UniProt:P39877

Recommended name:Phospholipase A2 group V

EC number:EC:3.1.1.4

Alternative names:(PLA2-10) (Phosphatidylcholine 2-acylhydrolase 5)

Cleaved into:

GeneID:5322

Gene names  (primary ):PLA2G5

Gene names  (synonym ):

Gene names  (ORF ):

Length:138

Mass:15674

Sequence:MKGLLPLAWFLACSVPAVQGGLLDLKSMIEKVTGKNALTNYGFYGCYCGWGGRGTPKDGTDWCCWAHDHCYGRLEEKGCNIRTQSYKYRFAWGVVTCEPGPFCHVNLCACDRKLVYCLKRNLRSYNPQYQYFPNILCS

Tissue specificity:Heart, placenta and less abundantly, in lung. Detected in the outer and inner plexiform layers of the retina (at protein level) (PubMed:22137173). Expressed in monocytes and macrophages (PubMed:25725101). {ECO:0000269|PubMed:22137173, ECO:0000269|PubMed:25725101}.

Induction:Up-regulated upon M2 macrophage polarization in response to IL4, CSF1 or IL10. {ECO:0000269|PubMed:25725101}.

Developmental stage:

Protein families:Phospholipase A2 family


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