CSAD_MOUSE   Q9DBE0


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UniProt:Q9DBE0

Recommended name:Cysteine sulfinic acid decarboxylase

EC number:EC 4.1.1.29

Alternative names:(Aspartate 1-decarboxylase) (Cysteine-sulfinate decarboxylase) (Sulfinoalanine decarboxylase)

Cleaved into:

GeneID:246277

Gene names  (primary ):Csad

Gene names  (synonym ):

Gene names  (ORF ):

Length:493

Mass:55145

Sequence:MADSKPLRTLDGDPVAVEALLQDVFGIVVDEAILKGTSASEKVCEWKEPEELKQLLDLELQSQGESREQILERCRTVIHYSVKTGHPRFFNQLFSGLDPHALAGRIITESLNTSQYTYEIAPVFVLMEEEVLKKLRALVGWNSGDGVFCPGGSISNMYAMNLARFQRYPDCKQRGLRALPPLALFTSKECHYSITKGAAFLGLGTDSVRVVKADERGRMIPEDLERQIILAEAEGSVPFLVSATSGTTVLGAFDPLDAIADVCQRHGLWFHVDAAWGGSVLLSRTHRHLLDGIQRADSVAWNPHKLLAAGLQCSALLLRDTSNLLKRCHGSQASYLFQQDKFYDVALDTGDKVVQCGRRVDCLKLWLMWKAQGGQGLERRIDQAFALTRYLVEEIKKREGFELVMEPEFVNVCFWFVPPSLRGKKESPDYSQRLSQVAPVLKERMVKKGTMMIGYQPHGTRANFFRMVVANPILAQADIDFLLGELELLGQDL

Tissue specificity:Expressed in kidney and liver not detected in lymphoid tissues and lung. Expressed in kidney, liver and brain. 7 and 4 times higher expression in kidney and liver than in brain, respectively. Low level of detection in skeletal muscle. Expressed in brain, olfactory bulb, liver, skeletal muscle and kidney with the highest expression in liver and lowest in skeletal muscle (at protein level) (PubMed:26327310). {ECO:0000269|PubMed:11997111, ECO:0000269|PubMed:26327310}.

Induction:

Developmental stage:Expression in the brain decreases with age as detected from 17 dpc to 12 months. {ECO:0000269|PubMed:26327310}.

Protein families:Group II decarboxylase family


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