S39A8_MOUSE Q91W10
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UniProt:Q91W10
Recommended name：Metal cation symporter ZIP8
EC number：
Alternative names：(Solute carrier family 39 member 8) (Zrt- and Irt-like protein 8) (ZIP-8)
Cleaved into：
GeneID：67547
Gene names (primary )：Slc39a8
Gene names (synonym )：Zip8
Gene names (ORF )：
Length：462
Mass：50082
Sequence：MAPGRAVAGLLLLAATSLGHPSEGPELAFSEDVLSVFGANRSLSAAQLGRLLERLGAASQQGALDLGQLHFNQCLSAEDIFSLHGFSNVTQITSSNFSAICPAILQQLNFHPCEDLRKHNAKPSLSEVWGYGFLSVTIINLASLLGLILTPLIKKSYFPKILTYFVGLAIGTLFSNAIFQLIPEAFGFNPKIDNYVEKAVAVFGGFYMLFFVERTLKMLLKTYGQNDHTHFRNDDFGSKEKTHQPKTLPLPAVNGVTCYANPAVTEPNGHIHFDTVSVVSLQDGKTEPSSCTCLKGPKLSEIGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVILLNAGMSTRQALLFNFLSACSCYVGLAFGILVGNNFAPNIIFALAGGMFLYISLADMFPEMNDMLREKVTGRQTDFTFFMIQNAGMLTGFTAILLITLYAGDIELQ
Tissue specificity：Ubiquitously expressed. {ECO:0000269|PubMed:15722412}.
Induction：Up-regulated in monocytes upon adhesion and recruitment to arteries (PubMed:30015240). Up-regulated by the proinflammatory cytokine interleukin-1 beta/IL1B (PubMed:24529376). {ECO:0000269|PubMed:24529376, ECO:0000269|PubMed:30015240}.
Developmental stage：Expressed in the developing heart by cardiac endothelial cells with a peak of expression at E12.5 and a decline to low levels in adult heart. {ECO:0000269|PubMed:29337306}.
Protein families：ZIP transporter (TC 2.A.5) family