TBX20_MOUSE Q9ES03
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UniProt:Q9ES03
Recommended name：T-box transcription factor TBX20
EC number：
Alternative names：(T-box protein 20)
Cleaved into：
GeneID：57246
Gene names (primary )：Tbx20
Gene names (synonym )：Tbx12
Gene names (ORF )：
Length：445
Mass：49096
Sequence：MEFTASPKPQLSSRANAFSIAALMSSGGPKEKEAAENTIKPLEQFVEKSSCAQPLGELTSLDAHAEFGGGGGSPSSSSLCTEPLIPTTPIIPSEEMAKIACSLETKELWDKFHELGTEMIITKSGRRMFPTIRVSFSGVDPESKYIVLMDIVPVDNKRYRYAYHRSSWLVAGKADPPLPARLYVHPDSPFTGEQLLKQMVSFEKVKLTNNELDQHGHIILNSMHKYQPRVHIIKKKDHTASLLNLKSEEFRTFIFPETVFTAVTAYQNQLITKLKIDSNPFAKGFRDSSRLTDIERESVESLIQKHSYARSPIRTYGEEDVLGEESQTTQSRGSAFTTSDNLSLSSWVSSSSSFPGFQHPQPLTALGTSTASIATPIPHPIQGSLPPYSRLGMPLTPSAIASSMQGSGPTFPSFHMPRYHHYFQQGPYAAIQGLRHSSAVMTPFV
Tissue specificity：Prominently expressed in the extraembryonic mesoderm, developing heart, eye analage and motor neurons of hindbrain and spinal cord. Expressed in extraembryonic tissues such as the amnion and allantois. {ECO:0000269|PubMed:11118890}.
Induction：
Developmental stage：Between 7.25 dpc and 8 dpc, expression detected in the extraembryonic mesoderm and contributes to amnion and chorion. Allantois expression persists until 10.5 dpc and continues into the umbilical cord. Expression is found throughout heart development. At 7.5 dpc, detected in the cardiogenic mesoderm, at 8.0 dpc-8.5, found in the cardiac crescent and looping heart tube and from 9.5 dpc, found in the forming four-chambered heart. At all stages, expression is much stronger in the myocardium than in the endocardium and expression extends from the cardiogenic into the lateral plate mesoderm. From 10.5 dpc on, weakly expressed in the periphery of the liver lobes, and in cells surrounding the aorta in the urogenital system. At 9.0 dpc, weakly expressed in the dorsal half of the optic vesicle. Later, expression spreads ventrally to enclose the entire neural retina at 11.5 dpc. At 9.0 dpc, expression is initiated in the hindbrain: first in the ventral region of rhombomere (r) 2 and 4, then in r7, r8 and in the cervical spinal cord. By 10.5 dpc, two ventral stripes of Tbx20 containing cells are continuous from r2 into the cervical spinal cord and expression is seen in two symmetrical patches of cell bodies in the mantle region of the ventral neural tube. At 11.5 dpc, expression follows the migration of motor neurons. {ECO:0000269|PubMed:11118890}.
Protein families：