Summary
| Production Name | Caspase 7 Rabbit Monoclonal Antibody |
| Description | Rabbit Monoclonal antibody |
| Host | Rabbit |
| Application | WB,IHC-P |
| Reactivity | Human |
Performance
| Conjugation | Unconjugated |
| Modification | Unmodified |
| Isotype | IgG |
| Clonality | Monoclonal Antibody |
| Form | Liquid |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Buffer | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Purification | Affinity Purification |
Immunogen
| Gene Name | CASP7 |
| Alternative Names | MCH3; CMH-1; LICE2; CASP-7; ICE-LAP3 |
| Gene ID | 840 |
| SwissProt ID | P55210 |
Application
| Dilution Ratio | WB: 1:500-1:1000 IHC: 1:50-1:100 |
| Molecular Weight | Calculated MW: 34 kDa; Observed MW: 34 kDa |
Background
Belongs to the peptidase C14A family. Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp--Gly-217' bond. Overexpression promotes programmed cell death.
Research Area
Cell Biology
