Summary
| Production Name | TDP 43 Rabbit Monoclonal Antibody |
| Description | Rabbit Monoclonal antibody |
| Host | Rabbit |
| Application | WB,IHC-F,IHC-P,ICC/IF,IP |
| Reactivity | Human,Mouse,Rat |
Performance
| Conjugation | Unconjugated |
| Modification | Unmodified |
| Isotype | IgG |
| Clonality | Monoclonal Antibody |
| Form | Liquid |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Buffer | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Purification | Affinity Purification |
Immunogen
| Gene Name | TARDBP |
| Alternative Names | ALS10; TDP-43 |
| Gene ID | 23435 |
| SwissProt ID | Q13148 |
Application
| Dilution Ratio | WB: 1:500-1:1000 IHC: 1:50-1:100 IF: 1:50-1:200 IP: 1:20 |
| Molecular Weight | Calculated MW: 45 kDa; Observed MW: 45 kDa |
Background
TDP43 (TAR DNA-binding protein 43) is involved in transcriptional regulation and exon splicing. While normal TDP43 is a nuclear protein, pathological TDP43 is a component of insoluble aggregates in patients with frontotemporal lobar degeneration (FTLD) and amyotrophic lateral sclerosis (ALS).
Research Area
Microbiology
