TAK1 Rabbit Monoclonal Antibody

TAK1 Rabbit Monoclonal Antibody

Size1:50μL Price1:$188
Size2:100μL Price2:$338
Size3:200μL Price3:$520
Application:WB,IHC-F,IHC-P,ICC/IF

Reactivity:Human
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge).
See other 26 conjugates.

Gene Name:MAP3K7
SKU: AMRe02664 Category: Recombinant Monoclonal Antibody Tags: , , , , , ,

Summary

Production Name

TAK1 Rabbit Monoclonal Antibody

Description

Rabbit Monoclonal antibody

Host

Rabbit

Application

WB,IHC-F,IHC-P,ICC/IF

Reactivity

Human

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Monoclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

Purification

Affinity Purification

 

Immunogen

Gene Name

MAP3K7

Alternative Names

MAP3K7; TAK1; Mitogen-activated protein kinase kinase kinase 7; Transforming growth factor-beta-activated kinase 1; TGF-beta-activated kinase 1

Gene ID

6885

SwissProt ID

O43318

 

Application

Dilution Ratio

WB: 1:500-1:1000 IHC: 1:50-1:100 IF: 1:50-1:200

Molecular Weight

Calculated MW: 67 kDa; Observed MW: 78 kDa

 

Background

Component of a protein kinase signal transduction cascade. Mediator of TRAF6 and TGF-beta signal transduction. Activates IKBKB and MAPK8 in response to TRAF6 signaling. Stimulates NF-kappa-B activation and the p38 MAPK pathway. In osmotic stress signaling, plays a major role in the activation of MAPK8/JNK, but not that of NF-kappa-B.