Cleaved-Caspase 1 Rabbit Polyclonal Antibody($99/20μL)

Cleaved-Caspase 1 Rabbit Polyclonal Antibody($99/20μL)

Cat: APRab03387
Size:20μL Price:$99
Size:50μL Price:$150
Size:100μL Price:$280

Size:200μL Price:$520
Application:WB,IHC,ICC/IF,ELISA

Reactivity:Human,Mouse,Rat
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge).
See other 26 conjugates.

Gene Name:CASP1 Category: Polyclonal Antibody Tags: , , , , , , , , ,

Summary

Production Name

Cleaved-Caspase 1 Rabbit Polyclonal Antibody

Description

Rabbit polyclonal Antibody

Host

Rabbit

Application

WB,IHC,ICC/IF,ELISA

Reactivity

Human,Mouse,Rat

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Polyclonal

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% protective protein and 0.02% sodium azide, pH 7.3.

Purification

Affinity Purification

 

Immunogen

Gene Name

CASP1

Alternative Names

CASP1; IL1BC; IL1BCE; Caspase-1; CASP-1; Interleukin-1 beta convertase; IL-1BC; Interleukin-1 beta-converting enzyme; ICE; IL-1 beta-converting enzyme; p45

Gene ID

834

SwissProt ID

P29466

 

Application

Dilution Ratio

WB 1:500-1:1000,IHC 1:50-1:100,ICC/IF 1:50-1:200,ELISA 1:5000-1:20000

Molecular Weight

Calculated MW: 45 kDa; Observed MW: 25 kDa

 

Background

Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis.

 

Research Area

Cell Biology

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