TIM 3 Rabbit Monoclonal Antibody

TIM 3 Rabbit Monoclonal Antibody

Size1:50μL Price1:$188
Size2:100μL Price2:$338
Application:WB, IHC-P, IP
Reactivity:Human,Mouse,Rat
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:TIM 3 SKU: AMRe87390 Category: Recombinant Monoclonal Antibody Tags: , , , , , , ,

Summary

Production Name

TIM 3 Rabbit Monoclonal Antibody

Description

Rabbit Monoclonal antibody

Host

Rabbit

Application

WB, IHC-P, IP

Reactivity

Human,Mouse,Rat

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Monoclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% protective protein . Stable for 12 months from date of receipt.

Purification

Affinity Purification

 

Immunogen

Gene Name

TIM 3

Alternative Names

TIM3; CD366; KIM-3; SPTCL; TIMD3; Tim-3; TIMD-3; HAVcr-2

Gene ID

84868

SwissProt ID

Q8TDQ0

 

Application

Dilution Ratio

WB: 1:1000 IHC-P: 1:200-1:1000 IP: 1:20-1:50

Molecular Weight

Calculated MW:33 kDa; Observed MW:45-70 kDa

 

Background

The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. [provided by RefSeq, Sep 2011]

 

Research Area

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