Cleaved-Caspase 8 Mouse Monoclonal Antibody

Cleaved-Caspase 8 Mouse Monoclonal Antibody

Size1:50μl Price1:$168
Size2:100μl Price2:$300
Size3:500μl Price3:$1200
SKU: AMM03879 Category: Mouse Monoclonal Antibody Tags: , , , , ,

Datasheet

Summary

Production Name

Cleaved-Caspase 8 Mouse Monoclonal Antibody

Description

Primary antibody

Host

Mouse

Application

WB,IHC,ICC/IF

Reactivity

Human,Mouse,Rat

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG1

Clonality

Monoclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Purification

Affinity Purified

 

Immunogen

Gene Name

CASP8

Alternative Names

CASP8; MCH5; Caspase-8; CASP-8; Apoptotic cysteine protease; Apoptotic protease Mch-5; CAP4; FADD-homologous ICE/ced-3-like protease; FADD-like ICE; FLICE; ICE-like apoptotic protease 5; MORT1-associated ced-3 homolog; MACH

Gene ID

841

SwissProt ID

Q14790

 

Application

Dilution Ratio

WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200

Molecular Weight

Calculated MW: 55 kDa; Observed MW: 18,43,57 kDa

 

Background

This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit.

 

Research Area

Cell Biology