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PIAS1+PIAS2 Rabbit Monoclonal Antibody

PIAS1+PIAS2 Rabbit Monoclonal Antibody

Cat: AMRe83949
Size:50μL Price:$168
Size:100μL Price:$300
Application:WB,IHC,ICC/IF,ICC,FC,IP
Reactivity:Human,Mouse,Rat
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:PIAS1+PIAS2 Category: Recombinant Monoclonal Antibody Tags:

Summary

Production Name

PIAS1+PIAS2 Rabbit Monoclonal Antibody

Description

Recombinant rabbit monoclonal antibody

Host

Rabbit

Application

WB,IHC,ICC/IF,ICC,FC,IP

Reactivity

Human,Mouse,Rat

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Monoclonal

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.05% protective protein and 50% glycerol.

Purification

Affinity Purification

 

Immunogen

Gene Name

PIAS1+PIAS2

Alternative Names

PIAS1; PIAS2;;PIAS1/2

Gene ID

SwissProt ID

O75925/O75928

 

Application

Dilution Ratio

WB 1:1000-1:2000,IHC 1:100-1:200,ICC/IF 1:50-1:200,ICC 1:50-1:200,FC 1:20-1:100,IP 1:20-1:50

Molecular Weight

Calculated MW: 72,68 kDa ; Observed MW: 76 kDa

 

Background

Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway, the p53 pathway and the steroid hormone signaling pathway.

 

Research Area

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