Summary
| Production Name | beta Catenin (5D6) Mouse Monoclonal Antibody |
| Description | Mouse Monoclonal Antibody |
| Host | Mouse |
| Application | WB |
| Reactivity | Human,Mouse,Rat |
Performance
| Conjugation | Unconjugated |
| Modification | Unmodified |
| Isotype | IgG1 |
| Clonality | Monoclonal Antibody |
| Form | Liquid |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. |
| Purification | Affinity Purification |
Immunogen
| Gene Name | CTNNB1 |
| Alternative Names | CTNNB1; CTNNB; OK/SW-cl.35; Catenin beta-1; Beta-catenin |
| Gene ID | 1499 |
| SwissProt ID | P35222 |
Application
| Dilution Ratio | WB: 1:500-1:1000 |
| Molecular Weight | Calculated MW: 85 kDa; Observed MW: 92 kDa |
Background
Beta-catenin is an adherens junction protein. Adherens junctions (AJs; also called the zonula adherens) are critical for the establishment and maintenance of epithelial layers, such as those lining organ surfaces. AJs mediate adhesion between cells, communicate a signal that neighboring cells are present, and anchor the actin cytoskeleton. In serving these roles, AJs regulate normal cell growth and behavior.
Research Area
Signal Transduction
