Caspase 10 Rabbit Monoclonal Antibody

Caspase 10 Rabbit Monoclonal Antibody

Cat: AMRe83876
Size:50μL Price:$168
Size:100μL Price:$300
Application:WB,IHC,FC,IP

Reactivity:Human
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge).
See other 26 conjugates.

Gene Name:Caspase 10
Category: Recombinant Monoclonal Antibody Tags:

Summary

Production Name

Caspase 10 Rabbit Monoclonal Antibody

Description

Recombinant rabbit monoclonal antibody

Host

Rabbit

Application

WB,IHC,FC,IP

Reactivity

Human

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Monoclonal

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.05% protective protein and 50% glycerol.

Purification

Affinity Purification

 

Immunogen

Gene Name

Caspase 10

Alternative Names

Apoptotic protease Mch4; CASP10; Caspase10; FLICE2; ICE like apoptotic protease 4; FADD-like ICE2;;Caspase 10

Gene ID

SwissProt ID

Q92851

 

Application

Dilution Ratio

WB 1:1000-1:2000,IHC 1:100-1:200,FC 1:20-1:100,IP 1:20-1:50

Molecular Weight

59 kDa

 

Background

Involved in the activation cascade of caspases responsible for apoptosis execution. Recruited to both Fas- and TNFR-1 receptors in a FADD dependent manner. May participate in the granzyme B apoptotic pathways. Cleaves and activates effector caspases CASP3, CASP4, CASP6, CASP7, CASP8 and CASP9. Hydrolyzes the small- molecule substrates, Tyr-Val-Ala-Asp-|-AMC and Asp-Glu-Val-Asp-|-AMC.

 

Research Area

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