Recombinant Human IL-13 (C-Fc)

Recombinant Human IL-13 (C-Fc)

Size1:10μg price1:$168
Size2:50μg price2:$465
Size3:500μg price3:$2380 SKU: PHH2151 Category: Cytokines Tags: ,

Datasheet

Name

Recombinant Human IL-13 (C-Fc)

Purity

Greater than 95% as determined by reducing SDS-PAGE

Endotoxin level

<1 EU/µg as determined by LAL test.

Construction

Recombinant Human Interleukin-13 is produced by our Mammalian expression system and the target gene encoding Gly21/xa0/xad/xa0Asn132 is expressed with a human IgG1 Fc tag at the C-terminus.

Accession #

AAK53823

Host

Human Cells

Species

Human

Predicted Molecular Mass

39.2 KDa

Buffer

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Form

Lyophilized

Shipping

The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.

Stability&Storage

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

Reconstitution

Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

 

 

 

Alternative Names

Interleukin-13; IL-13

 

Background

Interleukin-13 is also known as IL-13. It is a protein that in humans is encoded by the IL13 gene. Interleukin-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells.It is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils.

 

Note

For Research Use Only , Not for Diagnostic Use.

 

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