Recombinant Human PDGF-BB

Recombinant Human PDGF-BB

Size1:10μg price1:$168
Size2:50μg price2:$465
Size3:500μg price3:$2325 SKU: PEH1285 Category: Cytokines Tags: ,

Datasheet

Name

Recombinant Human PDGF-BB

Purity

Greater than 95% as determined by reducing SDS-PAGE

Endotoxin level

<0.2 EU/µg as determined by LAL test.

Construction

Recombinant Human Platelet-Derived Growth Factor BB is produced by our E.coli expression system and the target gene encoding Ser82-Thr190 is expressed.

Accession #

P01127

Host

E.coli

Species

Human

Predicted Molecular Mass

12.42 KDa

Buffer

Lyophilized from a 0.2 μm filtered solution of 20mM NaAc-HAc, pH 4.5.

Form

Lyophilized

Shipping

The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.

Stability&Storage

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

Reconstitution

Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

 

 

 

Alternative Names

PDGFBB; PDGF-BB

 

Background

Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma.Binding of PDGFB to its receptor elicits a variety of cellular responses. In addition, PDGFB is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound.

 

Note

For Research Use Only , Not for Diagnostic Use.

 

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