Recombinant Human IL-10RB (C-6His)

Recombinant Human IL-10RB (C-6His)

Size1:10μg price1:$66
Size2:50μg price2:$186
Size3:500μg price3:$930 SKU: PHH0859 Category: Cytokines Tags: ,

Datasheet

Name

Recombinant Human IL-10RB (C-6His)

Purity

Greater than 95% as determined by reducing SDS-PAGE

Endotoxin level

<1 EU/µg as determined by LAL test.

Construction

Recombinant Human Interleukin-10 Receptor Subunit Beta is produced by our Mammalian expression system and the target gene encoding Met20-Ser220 is expressed with a 6His tag at the C-terminus.

Accession #

Q08334

Host

Human Cells

Species

Human

Predicted Molecular Mass

24.5 KDa

Buffer

Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Form

Lyophilized

Shipping

The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.

Stability&Storage

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

Reconstitution

Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

 

 

 

Alternative Names

Interleukin-10 receptor subunit beta(IL10RB);Cytokine receptor class-II member 4;Cytokine receptor family 2 member 4;Interleukin-10 receptor subunit 2

 

Background

IL10RB is a single- pass type I membrane protein and contains two fibronectin type-III domains. It is an accessory chain which is essential for the active interleukin 10 receptor complex. Coexpression of IL10RB and IL10RA proteins has been shown to be required for IL10-induced signal transduction. Defects in IL10RB are the cause of inflammatory bowel disease type 25 (IBD25) which is a chronic, relapsing inflammation of the gastrointestinal tract with a complex etiology.

 

Note

For Research Use Only , Not for Diagnostic Use.

 

Related products