Smad5 Rabbit Monoclonal Antibody

Smad5 Rabbit Monoclonal Antibody

Size1:50μL Price1:$188 $99
Size2:100μL Price2:$338 $180
Application:WB,IHC-F,IHC-P,ICC/IF
Reactivity:Human,Rat
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:SMAD5 SKU: AMRe02614 Category: Recombinant Monoclonal Antibody Tags: , , , , , , , ,

Summary

Production Name

Smad5 Rabbit Monoclonal Antibody

Description

Rabbit Monoclonal antibody

Host

Rabbit

Application

WB,IHC-F,IHC-P,ICC/IF

Reactivity

Human,Rat

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Monoclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

Purification

Affinity Purification

 

Immunogen

Gene Name

SMAD5

Alternative Names

DKFZp781C1895; DKFZp781O1323; Dwfc; hSmad 5; hSmad5; JV5 1; JV5-1; MAD homolog 5; MAD mothers against decapentaplegic homolog 5; MAD; mothers against decapentaplegic homolog 5; MADH 5; MADH5; Mothers against decapentaplegic homolog 5; Mothers against DPP homolog 5; MusMLP; SMA and MAD related protein 5; SMAD 5; SMAD family member 5; SMAD mothers against DPP homolog 5; Smad5; Smad5; SMAD5_HUMAN.

Gene ID

4090

SwissProt ID

Q99717

 

Application

Dilution Ratio

WB: 1:500-1:1000 IHC: 1:50-1:100 IF: 1:50-1:200

Molecular Weight

Calculated MW: 52 kDa; Observed MW: 60 kDa

 

Background

Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. Smad5 is a receptor-regulated Smad (R-Smad). Smad5 is required for normal development of the cardiovascular system in vivo; lack of the Smad5 gene results in apoptosis of cardiac myocytes. 3 Upregulation of Smad5 has been reported to mediate apoptosis of gastric epithelial cells induced by Helicobacter pylori infection. Tissue specificity: Ubiquitous.

 

Research Area

Cardiovascular

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