Phospho-ERK1/2 (Thr202/Thr185) Rabbit Monoclonal Antibody

Phospho-ERK1/2 (Thr202/Thr185) Rabbit Monoclonal Antibody

Size1:50μL Price1:$188 $99
Size2:100μL Price2:$338 $180
Application:WB,IP
Reactivity:Human,Hamster,Rat
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:MAPK1/MAPK3 SKU: AMRe03751 Category: Recombinant Monoclonal Antibody Tags: , , , , , , , ,

Summary

Production Name

Phospho-ERK1/2 (Thr202/Thr185) Rabbit Monoclonal Antibody

Description

Rabbit Monoclonal antibody

Host

Rabbit

Application

WB,IP

Reactivity

Human,Hamster,Rat

 

Performance

Conjugation

Unconjugated

Modification

Phosphorylated

Isotype

IgG

Clonality

Monoclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

Purification

Affinity Purification

 

Immunogen

Gene Name

MAPK1/MAPK3

Alternative Names

MAPK1/MAPK3

Gene ID

5595/5594

SwissProt ID

P27361/P28482

 

Application

Dilution Ratio

WB: 1:500-1:1000 IP: 1:20

Molecular Weight

Calculated MW: 44,42 kDa; Observed MW: 44,42 kDa

 

Background

Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements.

 

Research Area

Epigenetics and Nuclear Signaling

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