RPGF5_RAT P83900
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UniProt:P83900
Recommended name:Rap guanine nucleotide exchange factor 5
EC number:
Alternative names:
Cleaved into:
GeneID:362799
Gene names (primary ):Rapgef5
Gene names (synonym ):Mrgef
Gene names (ORF ):
Length:580
Mass:67,601
Sequence:MGSSRLRVFDPPLERKDSAALSERQLPLPTFDVPYFKYIDEEDEDDEWGSRSQSSTEDDSVDSLLSDRYVVVSGTPEKILEHLLNDLHLAEVQHKETETLLDDFLLTYTVFMTTDDLCQALLRHYSAKKYQGEEENSDVPCRKRKVLHLVSQWISLYKDWLHEDEHSKMFLKTIYRNVLDDVYEYPILEKELKEFQKILGMHRRHTVDEYSPQKKNKALFHQFSLKENWLQHRGTVAETEEIFCHVYVTEHSYISVKAKVSSTAQEILKVVAEKLQRAEEDLALVAIMFSGEKHEFQPNDLAISKSLEASGRIYVYRKDLADTLNPFAENEESQQRSMRILGMNTWDLALELMSFDWSLFNSIHEQELIYFTFSRQGSGEHTVNLSLLLQRCNEVQLWVATEILLCSQLGKRVQLVKKFIKIAAHCKAQQNLNSFFAIVMGLNTASVSRLSQTWEKIPGKFKKLFSELESLTDPSLNHKAYRDAFKKMKPPKIPFMPLLLKDVTFIHEGNKTFLDNLVNFEKLHMIADTVRTLRHCRTNQFGSDMSPKEQQELKSYVNHLYVIDSQQALFELSHRLEPRA
Tissue specificity:In the embryo, expressed in young neurons of the developing telencephalon, diencephalon and hindbrain. Not expressed in progenitor cells in the ventricular zone. 1
Induction:Expression is first detected at embryonic day 13. 1 Publication
Developmental stage:Down-regulated in nerve growth factor-treated PC12 cells. 1
Protein families: