HTRA3_RAT   D3ZA76


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UniProt:D3ZA76

Recommended name:Serine protease HTRA3

EC number:EC:3.4.21.-

Alternative names:High-temperature requirement factor A3 Pregnancy-related serine protease

Cleaved into:

GeneID:

Gene names  (primary ):Htra3

Gene names  (synonym ):Prsp

Gene names  (ORF ):

Length:459

Mass:49,257

Sequence:MQARALLPATLATLATLAVSVLAREPPAAPCPARCDVSRCPSPRCPGGYVPDLCNCCLVCAASEGEPCGRPLDSPCGDSLECVRGVCRCRWTHTVCGTDGHTYADVCALQAASRRALQISGTPVRQLQKGACPSGLHQLTSPRYKFNFIADVVEKIAPAVVHIELFLRHPLFGRNVPLSSGSGFIMSEAGLIVTNAHVVSSSNTASGRQQLKVQLQNGDAYEATIQDIDKKSDIATILIHPNKKLPVLLLGHSADLRPGEFVVAIGSPFALQNTVTTGIVSTAQRDGKELGLRDSDMDYIQTDAIINYGNSGGPLVNLDGEVIGINTLKVAAGISFAIPSDRITRFLSEFQDKHVKDWKKRFIGIRMRTITPSLVEELKTANPDFPAVSSGIYVQEVVPNSPSQRGGIQDGDIIVKVNGRPLVDSSELQEAVLNESSLLLEVRRGNDDLLFSIMPEVVM

Tissue specificity:Expressed in the ovary, essentially in granulosa cells in a follicle-stage specific manner. Highest levels found in large luteinizing granulosa cells. 1

Induction:

Developmental stage:In the developing ovary, high expression, especially of the longer isoform, at 12 days of age after birth. Expression restricted to the interstitial cells surrounding the follicles. Levels are further increased during ovarian maturation. 1

Protein families:


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