HTRA3_RAT D3ZA76
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UniProt:D3ZA76
Recommended name:Serine protease HTRA3
EC number:EC:3.4.21.-
Alternative names:High-temperature requirement factor A3 Pregnancy-related serine protease
Cleaved into:
GeneID:
Gene names (primary ):Htra3
Gene names (synonym ):Prsp
Gene names (ORF ):
Length:459
Mass:49,257
Sequence:MQARALLPATLATLATLAVSVLAREPPAAPCPARCDVSRCPSPRCPGGYVPDLCNCCLVCAASEGEPCGRPLDSPCGDSLECVRGVCRCRWTHTVCGTDGHTYADVCALQAASRRALQISGTPVRQLQKGACPSGLHQLTSPRYKFNFIADVVEKIAPAVVHIELFLRHPLFGRNVPLSSGSGFIMSEAGLIVTNAHVVSSSNTASGRQQLKVQLQNGDAYEATIQDIDKKSDIATILIHPNKKLPVLLLGHSADLRPGEFVVAIGSPFALQNTVTTGIVSTAQRDGKELGLRDSDMDYIQTDAIINYGNSGGPLVNLDGEVIGINTLKVAAGISFAIPSDRITRFLSEFQDKHVKDWKKRFIGIRMRTITPSLVEELKTANPDFPAVSSGIYVQEVVPNSPSQRGGIQDGDIIVKVNGRPLVDSSELQEAVLNESSLLLEVRRGNDDLLFSIMPEVVM
Tissue specificity:Expressed in the ovary, essentially in granulosa cells in a follicle-stage specific manner. Highest levels found in large luteinizing granulosa cells. 1
Induction:
Developmental stage:In the developing ovary, high expression, especially of the longer isoform, at 12 days of age after birth. Expression restricted to the interstitial cells surrounding the follicles. Levels are further increased during ovarian maturation. 1
Protein families: