THRSP_RAT   P04143


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UniProt:P04143

Recommended name:Thyroid hormone-inducible hepatic protein

EC number:

Alternative names:

Cleaved into:

GeneID:

Gene names  (primary ):Thrsp

Gene names  (synonym ):S14

Gene names  (ORF ):

Length:150

Mass:17,009

Sequence:MQVLTKRYPKNCLLKVMDRYSAVVRNMEQVVMIPSLLRDVELSGSGGSVQDGAPDLYTYFTMLKSICVEVDHGLLPREEWQAKVAGNEGSEAENEAAETEEAEEDRLSEELDLEAQFHLHFSSLHHILTHLTQKAQEVTQKYQEMTGQVL

Tissue specificity:Highly expressed in liver, lactating mammary gland, epididymal, retroperitoneal and brown fat. Mainly expressed in tissues that synthesize triglycerides. 1

Induction:

Developmental stage:The mRNA levels in rat liver are up-regulated in response to thyroid hormone (T3) and a carbohydrate-rich diet. Up-regulated in liver at the time of weaning, when pups switch from a high-fat milk diet to having to synthesize their own fatty acids. Down-regulated by fasting. Levels of mRNA increase within 20 minutes of T3 administration. 3 s

Protein families:


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