OTX1_RAT Q63410
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UniProt:Q63410
Recommended name:Homeobox protein OTX1
EC number:
Alternative names:
Cleaved into:
GeneID:25646
Gene names (primary ):Otx1
Gene names (synonym ):
Gene names (ORF ):
Length:355
Mass:37,603
Sequence:MMSYLKQPPYGMNGLGLAGPAMDLLHPSVGYPATPRKQRRERTTFTRSQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQSGNGTKSRPVKKKSSPVRESSGSESSGQFTPPAVSSSASSSSSASSASANPAAAAAAGLGGNPVAAASSLSTPTASSIWSPASISPGSAPASVSVPEPLGAPSNASCMQRSVAAGAATAATSYPMSYGQGRSYGQGYPAPSSSYFGGVDCSSYLAPMHSHHHPHQLSPMAPSSMAGHHHHHPHAHHPLSQSSGHHHHHHHHHHHQGYGGSGLAFNSADCLDYKEPAAAAASSAWKLNFNSPDCLDYKDQASWRFQVL
Tissue specificity:Brain: restricted regions of the developing rostral brain including the presumptive cerebral cortex and olfactory bulbs; expressed in the developing olfactory, auricolar and ocular systems, including the covering of the optic nerve.
Induction:
Developmental stage:Expressed throughout the forebrain and midbrain during development, and in addition is also seen in discrete spatial and temporal domains in the developing cerebral cortex and cerebellum. Confined to a subpopulation of neurons in layers 5 and 6 within the adult cerebral cortex and during development expression is high in the progenitors of these deep-layer cells. Expressed in the developing cerebellum in spatially restricted regions of the external granular layer.
Protein families: