RTN1_RAT Q64548
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UniProt:Q64548
Recommended name:Reticulon-1
EC number:
Alternative names:
Cleaved into:
GeneID:
Gene names (primary ):Rtn1
Gene names (synonym ):Nsp
Gene names (ORF ):
Length:777
Mass:83,002
Sequence:MAAPPDLQDEPLSPANPGSQLFGGRGEGEEATPKGARPAQQDGEPAWGSGAGAGVVSSRGLCSGPARSPPVAMETASTGVAAVPDALDHSSSPTLKDGEGACYTSLISDICYPPREDSAYFTGILQKENGHITTSESPEELGTPGPSLPEVPGTEPHGLLSSDSGIEMTPAESTEVNKILADPLDQMKAEACKYIDITRPQEAKGQEEQSPGLEDKDLDFKDKDSEVSTKPEGVHAPNQPSPVEGKLIKDNLFEESTFAPYIDELSDEQHRMSLVTAPVKITLTEIGPPVMTATHETIPEKQDLCLKPSPDTVPTVTVSEPEDDSPGSVTPPSSGTEPSAAESQGKGSVSEDELIAAIKEAKGLSYETTESPRPVGQAADRPKVKARSGLPTIPSSLDQEASSAESGDSEIELVSEDPMASEDALPSGYVSFGHVSGPPPSPASPSIQYSILREEREAELDSELIIESCDASSASEESPKREQDSPPMKPGVLDAIREETSSRATEERAPSHQGPVEPDPILSFTPVTLQSRPEPSSGDGAPVPEPPKSQQQKPEEEAVSSSQSPAATEIPGPLGSDLVPPLPFFNKQKAIDLLYWRDIKQTGIVFGSFLLLLFSLTQFSVVSVVAYLALAALSATISFRIYKSVLQAVQKTDEGHPFKAYLELEITLSQEQIQKYTDCLQLYVNSTLKELRRLFLVQDLVDSLKFAVLMWLLTYVGALFNGLTLLLMAVVSMFTLPVVYVKHQAQVDQYLGLVRTHINTVVAKIQAKIPGAKRHAE
Tissue specificity:Expressed predominantly in central and peripheral nervous system of newborn and adult rats. Low levels have been also detected in heart, adrenal gland and spleen. Expression of isoform RTN1-B is restricted to particular neuronal types.
Induction:
Developmental stage:Detected at 10 dpc in the hindbrain and at 11 dpc in the forebrain. During the next 3 embryonic days the levels of RTN1-S increases and remains stable at 13 dpc in the hindbrain and at 14 dpc in the forebrain. The levels of RTN1-B does not change as significantly during development of the hindbrain.
Protein families: